Dalacin T. 1 tube of gel 30 gr.

Dalacin T. 1 tube of gel 30 gr.
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Price: $25.50
Availability: 2 - 3 Days
Manufacturer: Pfizer
Average Rating: Not Rated Write Review

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Description

PHARMACOLOGICAL ACTION: Microbiology: Although clindamycin phosphate is inactivein vitro, rapid in vivo hydrolysis converts this compound to the antibacterially active clindamycin. Clindamycin has been shown to have in vitro activity against isolates of Propionibacterium acnes. This may account for its usefulness in acne. Cross resistance has been demonstrated between clindamycin and lincomycin. Antagonism has been demonstrated between clindamycin and erythromycin. Clindamycin activity has been demonstrated in comedonal extracts from acne patients. The mean concentration of antibiotic activity in comedonal extracts was 597 micrograms/g of comedonal material. Clindamycin in vitro inhibits all Propionibacterium acnes cultures tested (MICs 0,4 micrograms/mL). Free fatty acids on skin surface have been decreased from approximately 14% to 2% following application of topical clindamycin. Following multiple topical applications of clindamycin phosphate at a concentration equivalent to 10 mg clindamycin per mL in an isopropyl alcohol and water solution, low levels of clindamycin are present in the serum (+ 3 ng/mL). INDICATIONS: DALACIN T Solution and DALACIN T Lotion are indicated in the treatment of acne vulgaris. CONTRA-INDICATIONS: DALACIN T Solution and DALACIN T Lotion are contra-indicated in individuals with a history of hypersensitivity to preparations containing clindamycin or lincomycin.

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Dalacin T. 1 tube of gel 30 gr. Dalacin T. 1 tube of gel 30 gr.
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