Rocaltrol, 0.25mcg 30 Caps
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Description
How does it work? Calcitriol (1, 25-dihydroxycholecalciferol) is a vitamin D metabolite which is normally produced in the kidneys from its immediate precursor, 25-hydroxycholecalciferol. In the normal situation it controls the intestinal absorption of calcium and phosphate and plays an important part in the regulation of bone mineralisation. In chronic renal failure, the kidneys produce insufficient calcitriol and this leads to abnormalities of calcium and phosphate metabolism. Oral administration of calcitriol to patients with chronic renal failure compensates for the reduced production of calcitriol. Consequently, intestinal malabsorption of calcium and phosphate and the resulting hypocalcaemia (low blood calcium levels) are improved, thereby reversing the signs and symptoms of bone disease. What is it used for? Osteoporosis in postmenopausal women The correction of abnormalities of calcium and phosphate metabolism in renal osteodystrophy
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