Generic Name: desonide topical (DEH so nide) Brand Names: Delonide, Desowen, Tridesilon What is the most important information I should know about desonide topical? • Do not use plastic bandages, dressings, or diapers that do not allow air to circulate to the area (occlusive dressings) unless your doctor directs you to do so. The use of occlusive dressings can greatly increase the amount of drug the body absorbs. If you do use an occlusive dressing, do not use it for more than 12 hours a day. • Do not use desonide topical to treat any area of the body that it is not prescribed for. This could be dangerous. • Desonide topical has not been approved for use by children. Children are more sensitive to the effects of desonide topical. Do not use desonide topical to treat a child unless it is prescribed by a doctor. What is desonide topical? • Desonide is a topical steroid. It reduces or inhibits the actions of chemicals in the body that cause inflammation, redness, and swelling. • Desonide is used to treat inflammation caused by a number of conditions such as allergic reactions, eczema, and psoriasis. • Desonide topical may also be used for purposes other than those listed in this medication guide.